Acepromazine (10 mg/ml) 10 to 20 mg, IV, once Sedation; relaxation of cervix prior to embryo transfer
Aminocaproic acid (Amicar®) (250 mg/ml) Loading dose: 40 mg/kg, IV, once Maintenance dose: 10 to 20 mg/kg, IV, q 6h Blocks plasminogen; anti-fibrinolytic (management of ruptured uterine artery)
Benztropine (Cogentin®) (1 mg/ml) 8 mg, IV, once Treatment of priapism in stallions or geldings (administer early in course of disease)
Cabergoline* 2 to 3 mg, PO, q 12h - q 24h for 500 kg mare Suppression of lactation
Calcium gluconate solution (23% solution) Add 100 to 150 mls to 1 liter of LRS; administer intravenously over 45 to 60 minutes Adjunct treatment for retained placenta in hypocalcemic mares
Cerumene™ (Squalane 25% solution)* Topical application Cerumenolytic agent; used to clean out clitoral sinuses if bacterial or fungal organisms are present and a potential nidus for subsequent reinfection
Clenbuterol (Ventipulmin®) (72.5 µg/ml) * 2.0 µg/kg, PO, q 12h Tocolytic agent (blocks uterine contractions)
Dexamethasone (2 mg/ml) 30 to 50 mg, IV or IM, once at time of mating or insemination Anti-inflammatory; management of persistent mating induced endometritis
Diazepam (Valium®) (5 mg/ml) 0.05 mg/kg, 5 to 7 minutes before breeding or collection Reduce anxiety in stallions with ejaculation problems
Firocoxib (Equioxx®) (20 mg/ml; injectable) (paste formulation in calibrated oral syringe and 57 mg tablet also available) 0.1 mg/kg, q 24 hrs (injectable) Loading dose: 0.3 mg/kg, PO, once Daily dose: 0.1 mg/kg, PO, q 24 hrs (oral paste) NSAID; selective COX-2 inhibitor; may be used in treatment of placentitis to reduce inflammation
Fluconazole (200 mg/tablet) 14 mg/kg, PO, loading dose, followed by 5 mg/kg q 24h Antifungal agent
Flunixin meglumine (Banamine®) (50 mg/ml) (paste formulation in calibrated oral syringe also available) 1.1 mg/kg, IV, once or PO, once (paste formulation) NSAID; anti-inflammatory, anti-prostaglandin; analgesic; administered prior to transfer of an embryo; treatment of placentitis
Imipramine (50 mg/tablet) 1.76 to 2.2 mg/kg, PO, administered 1 to 2 hrs prior to xylazine Chemical ejaculation of stallions; lowers the ejaculation threshold
Itraconazole* 3 to 5 mg/kg, PO, q 24h for 2 to 3 weeks or longer Antifungal agent
Meclofenamic Acid (Arquel®)* 2.2 mg/kg, PO, q 12h Prostaglandin inhibitor potentially used as adjunct therapy in embryo transfer
Mycobacterium cell wall fraction immunostimulant (Settle™) (1.5 ml vial) * 1.5 mls via intrauterine infusion or intravenous injection during early estrus (repeat as needed) Immunostimulant; administered to mares with endometritis caused by Streptococcus equi subsp. zooepidemicus; therapeutic goal is to enhance the innate humoral immune response in affected mares
N-Butylscopolammonium bromide (Buscopan®) (20 mg/ml) 0.08 to 0.12 mg/kg, IV (40 to 60 mg) administered 5 to 10 minutes prior to palpation Relaxation of rectal musculature (decrease rectal pressure)
N-Butylscopolammonium cream or gel (Buscopan®) Topical cream or gel Cervical relaxation; gel can be made by combining 5 mls of Buscopan® and 15 mls of sterile obstetrical lubricant or DMSO gel; applied to outside of cervix and within cervical lumen
Naloxone (Narcan®)* 12 to 20 mg, IV (shock dose: 0.03 mg/kg, IV) Postpartum hemorrhage
Pentoxifylline (400 mg/tablet) * 8.4 mg/kg, PO, q 6h to q 8h Management of placentitis
Pergolide mesylate (Prascend®) (1 mg/tablet) 0.002 to 0.004 mg/kg (1 to 2 mg total dose), PO, q 24h for 500 kg mare Treatment of Equine Cushing’s Disease; suppression of lactation
Perphenazine (Trifafon®)* 0.3 to 0.5 mg/kg, PO, q 8h Fescue toxicosis
Phenylephrine HCL (0.25 %) (Preparation H®) Topical as needed Vasoconstrictive agent; topical treatment for bleeding vaginal vericose veins
Propanetheline bromide 30 mg, IV, once Rectal relaxation; wait 5 to 10 minutes after administration prior to palpation
Reserpine (Serpasil®)* 2.5 mg, PO, q 24h for 7 to 10 days Management of agalactia, behavioral modification
Sodium Bicarbonate (8.4%) 10 to 20 mls added to aminoglycoside antibiotic prior to intrauterine infusion Used to balance pH of aminoglycoside antibiotics (i.e. gentamicin)
Xylazine (100 mg/ml) 0.44 to 0.66 mg/kg, IV, 1 to 2 hours after imipramine Chemical ejaculation of stallions; sedation

*medication reported to be used at other facilities; not in use at CSU