MISCELLANEOUS MEDICATIONS |
||
|---|---|---|
| MEDICATION | DOSAGE, ROUTE, FREQUENCY | INDICATIONS |
| Acepromazine (10 mg/ml) | 10 to 20 mg, IV, once | Sedation; relaxation of cervix prior to embryo transfer |
| Aminocaproic acid (Amicar®) (250 mg/ml) |
Loading dose: 40 mg/kg, IV, once
Maintenance dose: 10 to 20 mg/kg, IV, q 6h
|
Blocks plasminogen; anti-fibrinolytic (management of ruptured uterine artery) |
| Benztropine (Cogentin®) (1 mg/ml) | 8 mg, IV, once | Treatment of priapism in stallions or geldings (administer early in course of disease) |
| Cabergoline* | 2 to 3 mg, PO, q 12h - q 24h for 500 kg mare | Suppression of lactation |
| Calcium gluconate solution (23% solution) | Add 100 to 150 mls to 1 liter of LRS; administer intravenously over 45 to 60 minutes | Adjunct treatment for retained placenta in hypocalcemic mares |
| Cerumene™ (Squalane 25% solution)* | Topical application | Cerumenolytic agent; used to clean out clitoral sinuses if bacterial or fungal organisms are present and a potential nidus for subsequent reinfection |
| Clenbuterol (Ventipulmin®) (72.5 µg/ml) * |
2.0 µg/kg, PO, q 12h
|
Tocolytic agent (blocks uterine contractions) |
| Dexamethasone (2 mg/ml) | 30 to 50 mg, IV or IM, once at time of mating or insemination | Anti-inflammatory; management of persistent mating induced endometritis |
| Diazepam (Valium®) (5 mg/ml) |
0.05 mg/kg, 5 to 7 minutes before breeding or collection
|
Reduce anxiety in stallions with ejaculation problems |
| Firocoxib (Equioxx®) (20 mg/ml; injectable) (paste formulation in calibrated oral syringe and 57 mg tablet also available) |
0.1 mg/kg, q 24 hrs (injectable)
Loading dose: 0.3 mg/kg, PO, once
Daily dose: 0.1 mg/kg, PO, q 24 hrs (oral paste)
|
NSAID; selective COX-2 inhibitor; may be used in treatment of placentitis to reduce inflammation |
| Fluconazole (200 mg/tablet) |
14 mg/kg, PO, loading dose, followed by 5 mg/kg q 24h
|
Antifungal agent |
| Flunixin meglumine (Banamine®) (50 mg/ml) (paste formulation in calibrated oral syringe also available) |
1.1 mg/kg, IV, once
or
PO, once (paste formulation)
|
NSAID; anti-inflammatory, anti-prostaglandin; analgesic; administered prior to transfer of an embryo; treatment of placentitis |
| Imipramine (50 mg/tablet) |
1.76 to 2.2 mg/kg, PO, administered 1 to 2 hrs prior to xylazine
|
Chemical ejaculation of stallions; lowers the ejaculation threshold |
| Itraconazole* |
3 to 5 mg/kg, PO, q 24h for 2 to 3 weeks or longer
|
Antifungal agent |
| Meclofenamic Acid (Arquel®)* |
2.2 mg/kg, PO, q 12h
|
Prostaglandin inhibitor potentially used as adjunct therapy in embryo transfer |
| Mycobacterium cell wall fraction immunostimulant (Settle™) (1.5 ml vial) * | 1.5 mls via intrauterine infusion or intravenous injection during early estrus (repeat as needed) | Immunostimulant; administered to mares with endometritis caused by Streptococcus equi subsp. zooepidemicus; therapeutic goal is to enhance the innate humoral immune response in affected mares |
| N-Butylscopolammonium bromide (Buscopan®) (20 mg/ml) |
0.08 to 0.12 mg/kg, IV (40 to 60 mg) administered 5 to 10 minutes prior to palpation
|
Relaxation of rectal musculature (decrease rectal pressure) |
| N-Butylscopolammonium cream or gel (Buscopan®) | Topical cream or gel | Cervical relaxation; gel can be made by combining 5 mls of Buscopan® and 15 mls of sterile obstetrical lubricant or DMSO gel; applied to outside of cervix and within cervical lumen |
| Naloxone (Narcan®)* |
12 to 20 mg, IV (shock dose: 0.03 mg/kg, IV)
|
Postpartum hemorrhage |
| Pentoxifylline (400 mg/tablet) * |
8.4 mg/kg, PO, q 6h to q 8h
|
Management of placentitis |
| Pergolide mesylate (Prascend®) (1 mg/tablet) |
0.002 to 0.004 mg/kg (1 to 2 mg total dose), PO, q 24h for 500 kg mare
|
Treatment of Equine Cushing’s Disease; suppression of lactation |
| Perphenazine (Trifafon®)* |
0.3 to 0.5 mg/kg, PO, q 8h
|
Fescue toxicosis |
| Phenylephrine HCL (0.25 %) (Preparation H®) | Topical as needed | Vasoconstrictive agent; topical treatment for bleeding vaginal vericose veins |
| Propanetheline bromide | 30 mg, IV, once | Rectal relaxation; wait 5 to 10 minutes after administration prior to palpation |
| Reserpine (Serpasil®)* | 2.5 mg, PO, q 24h for 7 to 10 days | Management of agalactia, behavioral modification |
| Sodium Bicarbonate (8.4%) | 10 to 20 mls added to aminoglycoside antibiotic prior to intrauterine infusion | Used to balance pH of aminoglycoside antibiotics (i.e. gentamicin) |
| Xylazine (100 mg/ml) |
0.44 to 0.66 mg/kg, IV, 1 to 2 hours after imipramine
|
Chemical ejaculation of stallions; sedation |
*medication reported to be used at other facilities; not in use at CSU
