SYSTEMIC ANTIBIOTICS

MEDICATION DOSAGE, ROUTE, FREQUENCY INDICATIONS
Ceftiofur sodium (Naxcel®) (50 mg/ml) 2.2 to 4.4 mg/kg, IV or IM, q 24h Antibiotic (broad spectrum); used in equine reproduction for treatment of bacterial endometritis
Ceftiofur crystalline free acid (Excede®) (200 mg/ml) 6.6 mgCE/kg, IM; 2 doses 4 days apart Antibiotic (broad spectrum); used in equine reproduction for systemic treatment of bacterial endometritis
Enrofloxacin (Baytril®) (100 mg/ml) 5 mg/kg, IV, q 24 hours Antibiotic (broad spectrum); used in equine reproduction for treatment of bacterial endometritis, specifically for resistant Pseudomonas sp.; Note: intra-uterine therapy is associated with severe necrosis and is not recommended
Gentamicin (100 mg/ml) 6.6 mg/kg, IV, q 24h Antibiotic (Gram-negative spectrum); used in equine reproduction for treatment of bacterial endometritis, chronic administration or administration to a dehydrated horse may result in acute renal failure
Penicillin (Procaine) (300,000 units per ml) 22,000 IU/kg, IM, q 12h Antibiotic (Gram-positive spectrum); used in equine reproduction for treatment of bacterial endometritis; severe procaine reactions may observed after administration to susceptible horses
Trimethoprim-Sulfamethoxasole (960 mg tablets) 30 mg/kg, PO, q 12h Antibiotic (broad spectrum); used in equine reproduction for treatment of mares with chronic endometritis or pregnant mares with bacterial placentitis

*medication reported to be used at other facilities; not in use at CSU